Head and Neck Tumours: Salivary Glands, Viruses and MEN2 | Part 2 | 頭頸腫瘤 | OET Music

Dr Allison Lu · Pip & Barnaby · Medical English

本頁提供本曲完整英文歌詞與影片搭配的繁中醫學提示。歌詞保留原演唱文字;遇到過度簡化或舊門檻,請搭配下方提示與原始資料閱讀。這是概念學習材料,不替代個別醫療評估。

Lyrics · 完整歌詞

The rest of the head and neck follows similar rules.
Thymoma accompanies myasthenia gravis, and thymic carcinoma is usually squamous.
Pleomorphic adenoma, the commonest salivary tumour, contains chondromyxoid stroma,
whereas Warthin tumour shows oncocytic epithelium with lymphoid stroma
and is linked to smoking.
Mucoepidermoid carcinoma, not squamous carcinoma, is the commonest salivary malignancy.
Nasopharyngeal carcinoma is driven by Epstein-Barr virus,
oropharyngeal carcinoma by HPV-16 with a better prognosis,
and erythroplakia carries a far higher malignant risk than leukoplakia.

All medullary thyroid carcinomas arise from C cells, secrete calcitonin,
deposit amyloid and ignore radioiodine.
Is the RET mutation germline?
Then MEN2 is present, and phaeochromocytoma is excluded before any thyroid surgery.
On the three axes, primary hyperparathyroidism reads high calcium and low phosphate,
secondary reads low calcium and high phosphate.
Lumps aside,
the glands behind the thyroid keep calcium in and phosphate out,
so their loss brings tetany treated with calcium gluconate.


All medullary thyroid carcinomas arise from C cells, secrete calcitonin,
deposit amyloid and ignore radioiodine.
Is the RET mutation germline?
Then MEN2 is present, and phaeochromocytoma is excluded before any thyroid surgery.
On the three axes, primary hyperparathyroidism reads high calcium and low phosphate,
secondary reads low calcium and high phosphate.
Lumps aside,
the glands behind the thyroid keep calcium in and phosphate out,
so their loss brings tetany treated with calcium gluconate.

Medical Notes · 醫學學習提示

  1. 頭頸器官定位示意;色標不是病灶或實際腺體邊界
  2. 胸腺瘤可合併重症肌無力;胸腺癌最常見鱗狀型
  3. 多形性腺瘤常見軟骨黏液樣間質
  4. Warthin 瘤具有嗜酸性上皮與淋巴樣間質
  5. Warthin 瘤與吸菸相關
  6. 黏液表皮樣癌是最常見唾液腺惡性腫瘤之一
  7. 鼻咽癌,尤其非角化型,常與 EBV 相關
  8. HPV 相關口咽癌常見 HPV-16;並非所有口咽癌皆相關
  9. 口腔紅斑常有較高異生或癌症風險,須專科評估
  10. 髓質癌源自 C 細胞;降鈣素分泌並非每例皆明顯
  11. 可見類澱粉沉積,非必備;放射碘不適用
  12. 胚系 RET 須判定是否為致病變異
  13. 致病變異提示 MEN2;術前評估嗜鉻細胞瘤
  14. 原發副甲亢常高鈣低磷;也有正常血鈣型
  15. 腎病性次發副甲亢:鈣可低或正常,早期磷可正常
  16. 除腫塊診斷,也要注意荷爾蒙功能
  17. PTH 促腎臟保鈣排磷;合併腎功能判讀
  18. 嚴重或有症狀低鈣:心電監測下靜脈葡萄糖酸鈣

References