Colorectal Review: Polyps, Cancer and Diverticular Disease | Part 2 | 大腸 | OET Music

Dr Allison Lu · Pip & Barnaby · Medical English

本頁提供本曲完整英文歌詞與影片搭配的繁中醫學提示。歌詞保留原演唱文字；遇到過度簡化或舊門檻，請搭配下方提示與原始資料閱讀。這是概念學習材料，不替代個別醫療評估。

Lyrics · 完整歌詞

The central distinctions can be recalled as follows.

All colorectal cancers travel the APC,
KRAS and TP53 sequence over five to ten years,
which is why removing adenomas prevents cancer.
Is the disease stage III or stage IV?
Stage III receives FOLFOX or CAPOX alone, while stage IV adds bevacizumab,
or cetuximab for RAS wild-type left-sided tumours.
On the dentate line everything changes: portal drainage,
autonomic nerves and painless internal haemorrhoids above, caval drainage,
the pudendal nerve and painful external haemorrhoids below.
Luminal narrowness and diverticula, not a thin wall, make the sigmoid perforate,
and Hinchey III or IV peritonitis means emergency surgery.


All colorectal cancers travel the APC,
KRAS and TP53 sequence over five to ten years,
which is why removing adenomas prevents cancer.
Is the disease stage III or stage IV?
Stage III receives FOLFOX or CAPOX alone, while stage IV adds bevacizumab,
or cetuximab for RAS wild-type left-sided tumours.
On the dentate line everything changes: portal drainage,
autonomic nerves and painless internal haemorrhoids above, caval drainage,
the pudendal nerve and painful external haemorrhoids below.
Luminal narrowness and diverticula, not a thin wall, make the sigmoid perforate,
and Hinchey III or IV peritonitis means emergency surgery.

Medical Notes · 醫學學習提示

  1. 大腸癌、血流與憩室重點；圖為正常大腸
  2. 更正：並非所有大腸癌都經 APC 途徑
  3. 基因順序與進展時間不固定，另有鋸齒狀及 MMR 缺陷途徑
  4. 切除腺瘤可降低癌症風險，仍須依病理安排追蹤
  5. 第三期有區域淋巴結轉移；第四期有遠端轉移
  6. 第三期術後常用輔助化療；第四期選藥依分子與病況
  7. 左側 RAS 野生型常適用；特定 KRAS 合併標靶療法另論
  8. 齒狀線是重要分界，門脈與體循環間仍有交通
  9. 上方對切割痛較不敏感；內痔併發症仍可能疼痛
  10. 下方由體神經傳遞痛覺，但外痔不一定都疼痛
  11. 憩室壁結構薄弱與發炎可致穿孔，不能只用腸徑解釋
  12. 廣泛化膿或糞便性腹膜炎須緊急外科處置

References