APL Review: Patient Communication and Differentiation Syndrome | Part 2 | 白血病 | OET Music

Dr Allison Lu · Pip & Barnaby · Medical English

本頁提供本曲完整英文歌詞與影片搭配的繁中醫學提示。歌詞保留原演唱文字;遇到過度簡化或舊門檻,請搭配下方提示與原始資料閱讀。這是概念學習材料,不替代個別醫療評估。

Lyrics · 完整歌詞

Communication is part of the emergency.
The patient hears the word leukaemia and asks about death;
the honest answer is that most patients are cured
and that the first two weeks carry the danger.
The disease is an acquired change in one marrow cell,
not an inherited one, so children are not at risk.
Speed is explained as protection rather than panic.

All patients with suspected acute promyelocytic leukaemia receive all-trans retinoic acid before genetic confirmation.
Is the prothrombin time prolonged,
fibrinogen low and D-dimer high in a bleeding young adult?
Look for faggot cells.
On induction, keep platelets above 30 to 50 and fibrinogen above 1.5,
and treat differentiation syndrome with dexamethasone.
Lucid rule for tumour lysis: hydrate, give allopurinol,
and reserve rasburicase for high risk patients without G6PD deficiency.


All patients with suspected acute promyelocytic leukaemia receive all-trans retinoic acid before genetic confirmation.
Is the prothrombin time prolonged,
fibrinogen low and D-dimer high in a bleeding young adult?
Look for faggot cells.
On induction, keep platelets above 30 to 50 and fibrinogen above 1.5,
and treat differentiation syndrome with dexamethasone.
Lucid rule for tumour lysis: hydrate, give allopurinol,
and reserve rasburicase for high risk patients without G6PD deficiency.

Medical Notes · 醫學學習提示

  1. 同理溝通,是急症照護的一部分
  2. 誠實說明病情與治療
  3. 多數患者可治癒;早期風險仍需重視
  4. 最初兩週:密切監測出血風險
  5. 骨髓細胞後天發生的改變
  6. 此後天病變不會因此遺傳給子女
  7. 說明迅速處置的保護意義
  8. 懷疑 APL:ATRA 不等待基因確認
  9. 留意 PT 延長
  10. Fibrinogen ↓ D-dimer ↑ 出血警訊
  11. 含 Auer rods 束的異常前骨髓細胞
  12. Platelets >30–50 ×10⁹/L | Fibrinogen >1.5 g/L
  13. 分化症候群:立即評估並給予 dexamethasone
  14. 補液與 allopurinol;依風險調整
  15. Rasburicase:評估高風險患者;G6PD 缺乏禁用

References