Neuro Localisation Review: Myelin, Gaze, Corneal Reflex and Roots | Part 2 | 神經定位 | OET Music

Dr Allison Lu · Pip & Barnaby · Medical English

本頁提供本曲完整英文歌詞與影片搭配的繁中醫學提示。歌詞保留原演唱文字；遇到過度簡化或舊門檻，請搭配下方提示與原始資料閱讀。這是概念學習材料，不替代個別醫療評估。

Lyrics · 完整歌詞

All myelin in the central nervous system comes from oligodendrocytes
and is cleared by microglia,
whereas Schwann cells both myelinate and repair peripheral nerves.
Is the second messenger cAMP or calcium?
Beta receptors raise cAMP through Gs,
alpha-1 and M3 raise calcium through Gq,
and cGMP belongs to nitric oxide, never beta.
On gaze,
a destroyed frontal eye field lets the eyes drift toward the lesion
and a destroyed pontine centre drives them away;
the corneal reflex runs V1 in, VII out.
Lumbar disc herniation in the paracentral position compresses the traversing root below,
so L4-5 takes L5 and L5-S1 takes S1,
and only a far-lateral herniation catches the exiting root.

All myelin in the central nervous system comes from oligodendrocytes
and is cleared by microglia,
whereas Schwann cells both myelinate and repair peripheral nerves.
Is the second messenger cAMP or calcium?
Beta receptors raise cAMP through Gs,
alpha-1 and M3 raise calcium through Gq,
and cGMP belongs to nitric oxide, never beta.
On gaze,
a destroyed frontal eye field lets the eyes drift toward the lesion
and a destroyed pontine centre drives them away;
the corneal reflex runs V1 in, VII out.
Lumbar disc herniation in the paracentral position compresses the traversing root below,
so L4-5 takes L5 and L5-S1 takes S1,
and only a far-lateral herniation catches the exiting root.

Medical Notes · 醫學學習提示

  1. 中樞髓鞘由少突膠細胞形成
  2. 小膠細胞是清除髓鞘碎屑的重要角色，並非唯一
  3. 許旺細胞形成周邊髓鞘，也支持神經再生
  4. 受體訊號可經 cAMP 或細胞內鈣等第二訊息傳遞
  5. β 受體主要經 Gs 增加 cAMP
  6. α1 與 M3 主要經 Gq 增加細胞內鈣訊號
  7. 一氧化氮可增加 cGMP；利鈉肽也可啟動此路徑
  8. 凝視偏向須結合病灶位置與性質
  9. 破壞性額葉眼動區病灶可使眼偏向病側
  10. 橋腦凝視中樞破壞可使眼偏離病側
  11. 角膜反射：V1 傳入、VII 傳出；圖為眼球解剖
  12. 腰椎旁中央突出常壓迫向下通過的神經根
  13. 典型：L4–5 影響 L5；L5–S1 影響 S1
  14. 椎間孔內或遠外側突出皆可影響出口神經根

References